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J Korean Endocr Soc. 2008 Dec;23(6):430-437. Korean. Case Report.
Won HK , Lee MJ , Park JH , Song IG , Lee GE , Jeong JH , Cheon JY , Sul HJ , Lim DM , Park KY .
Department of Internal Medicine, Konyang University Medical School, Daejeon, Korea.
Department of Pathology, Konyang University Medical School, Daejeon, Korea.

The diffuse sclerosing variant of papillary thyroid carcinoma (DSPTC) is a rare histological subtype characterized by diffuse involvement of one or both thyroid lobes, widespread lymphatic permeation, prominent fibrosis, squamous metaplasia, abundant psammoma body and lymphatic infiltration. This subtype usually occurs in young female, and exhibits a higher frequency of cervical and distant metastasis. DSPTC clinically resembles Hashimoto's thyroiditis, and often delays the correct diagnosis. We experienced two patients with DSPTC: the one patient presented with a neck mass lasting for a month, and in the other patient, a thyroid lesion was incidentally found during a medical examination.

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