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J Korean Endocr Soc. 2007 Jun;22(3):235-240. Korean. Case Report. https://doi.org/10.3803/jkes.2007.22.3.235
Yoo SH , Lim KJ , Lee SH , Kim JH , Hong SH , Cho JH , Jung CK , Kwon HS , Yoon KH , Kim MS , Cha BY , Son HY .
Department of Internal Medicine, The Catholic University of Korea, College of Medicine, Korea.
Department of Pathology, The Catholic University of Korea, College of Medicine, Korea.
Department of Otolaryngology, The Catholic University of Korea, College of Medicine, Korea.
Abstract

The origin of medullary thyroid carcinoma and papillary thyroid carcinoma are embryogenically different, so these tumors have been thought to be independent of each other. We experienced a case of concurrent medullary and papillary thyroid carcinoma in one patient. The patient underwent total thyroidectomy and both two tumors were located at different lobes, respectively. Both tumors showed their own characteristic pathologic and immunohistochemical findings. The patient's elevated calcitonin level returned to the normal range after operation and there has been no evidence of recurrence. It is still controversial whether the concurrency is just coincidental or it arises from activation of a common tumorigenic pathway.

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