Korean J Gastroenterol.
2007 Dec;50(6):402-406.
A Case of Sclerosing Cholangitis Showing Response to Prednisolone
- Affiliations
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- 1Department of Internal Medicine, Keimyung University College of Medicine, Daegu, Korea. seenae99@dsmc.or.kr
- 2Department of Diagnostic Radiology,Keimyung University College of Medicine, Daegu, Korea.
- 3Department of Pathology, Keimyung University College of Medicine, Daegu, Korea.
Abstract
- Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by progressive fibrosis and destruction of intra- and extrahepatic bile ducts resulting in hepatic failure and death. Only the liver transplantation is the possible treatment for patients to survive. There has been a few reports that steroid is an effective treatment in autoimmune variant sclerosing cholangitis, which is thought to be a familial diseases with different etiology, and steroid responsive biliary strictures be named as immunoglobulin G4 (IgG4)-associated cholangitis (IAC). There is no reliable data regarding effective steroid treatment in autoimmue variant sclerosing cholangitis in Korea. We report a case of 32-year-old male with sclerosing cholangitis, who was diagnosed by endoscopic retrograde cholangiopancreatography (ERCP) and liver biopsy, showing favorable response to prednisolone therapy.
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