Korean J Gastroenterol.  2008 Aug;52(2):106-109.

Endoscopic Resection of a Giant Duodenal Brunner's Gland Adenoma

• Kang BK
• Park NS
• Jin DH
• Ahn TH
• Park MB
• Lee KJ
• Han YJ
• Park HJ

Abstract

Brunner's gland adenoma is a rare tumor of duodenum. Patients are usually aymptomatic and most are discovered incidentally during the upper gastrointestinal (GI) series or esophagogastroduodenoscopy. These lesions are most commonly located in the duodenal bulb and clinical manifestations are variable. In symptomatic patients, the most common manifestations are GI hemorrhage and duodenal obstruction. On histologic examination, Brunner's gland adenoma that causes clinical symptoms is composed of hyperplastic Brunner's glands and contains mostly an admixture of glandular, adipose, and muscular tissues. We report a case of large Brunner's gland adenoma causing upper gastrointestinal hemorrhage in a 47-year-old woman which was successfully removed by endoscopic resection without complications such as bleeding or perforation. Microscopically, it was entirely composed of variable Brunner's glands.

Keyword

Gastrointestinal hemorrhage; Brunner's gland adenoma; Endoscopic resection

MeSH Terms

Adenoma/complications/*pathology/surgery
Brunner Glands/*pathology/surgery
Duodenal Neoplasms/complications/*pathology/surgery
Duodenoscopy
Female
Gastrointestinal Hemorrhage/etiology
Humans
Middle Aged