Korean J Intern Med.  2006 Dec;21(4):275-278. 10.3904/kjim.2006.21.4.275.

A case report of nonepisodic angioedema with eosinophilia in a Korean patient and a review of the Korean literature

• Jang JS
• Kim CH
• Kim SS
• Oh JE
• Park YB
• Lee JY
• Mo EK

• KMID: 759865
• DOI: http://doi.org/10.3904/kjim.2006.21.4.275

Abstract

Episodic angioedema with eosinophilia (EAE) is characterized by recurrent angioedema, peripheral eosinophilia, elevated serum IgM, fever, weight gain, and a benign course lacking any internal organ involvement. Dozens of cases of the nonepisodic variant (NEAE), which is limited to a single attack, have been reported in Japan. These NEAE cases normally have been less severe than the episodic type. In this paper, we describe the case of a Korean patient whose clinical and laboratory findings were consistent with NEAE, and review five other cases of EAE and NEAE reported in the Korean literature. The Korean NEAE cases outlined in this paper demonstrate that, as in Japan, NEAE is not uncommon in Korea, and also suggest that this disease exhibits a cultural predilection for Asian populations.

Keyword

Angioedema; Eosinophilia

MeSH Terms

Skin/pathology
Korea
Humans
Follow-Up Studies
Female
Eosinophilia/*complications/pathology
Diagnosis, Differential
Biopsy
Angioneurotic Edema/*complications/pathology
Adult