Korean J Intern Med.  2003 Sep;18(3):196-198.

Dermatomyositis Developing in the first Trimester of Pregnancy

Affiliations
  • 1Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, Korea. chsuh@ajou.ac.kr
  • 2Department of Anatomic pathology, Ajou University School of Medicine, Suwon, Korea.

Abstract

Dermatomyositis in pregnancy is rare. Pregnancy may be a precipitating factor at the onset or may develop during the course of dermatomyositis, which would exacerbate disease activity. In this study, we report a 22-year-old female patient who developed generalized skin rash and progressive muscle weakness in the twelfth week of pregnancy. She was diagnosed with dermatomyositis and underwent therapeutic abortion, due to the high fetal mortality rate of the disease when developed in the first trimester. Her symptoms improved with treatment of intravenous immunoglobulin and a high dose of corticosteroids.

Keyword

Dermatomyositis; Pregnancy

MeSH Terms

Adult
Anti-Inflammatory Agents/therapeutic use
Dermatomyositis/drug therapy/*etiology/pathology
Female
Human
Immunoglobulins, Intravenous/*administration & dosage
Prednisolone/therapeutic use
Pregnancy
*Pregnancy Complications
Pregnancy Trimester, First
Skin/pathology
Treatment Outcome
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