Korean J Intern Med.  2000 Dec;15(3):245-249.

A Case of Primary Intestinal T-Cell Lymphoma Involving Entire Gastrointestinal Tract: Esophagus to Rectum

• Ahn MJ
• Park YW
• Han D
• Choi JH
• Shin SJ
• Yoon BC
• Choi HS
• Lee YY
• Jung TJ
• Choi IY
• Park MH
• Kim IS

Abstract

Primary intestinal T-cell lymphoma is a rare disease entity, which is approximately 10% to 25% of intestinal lymphomas, and most of the lymphomas occur in the small intestine. We report here a case of a 56-year-old woman who has been suffering from chronic diarrhea and weight loss for 6 months. Abdominal CT scan and small bowel series showed diffuse wall thickening of the small bowel. Gastroscopic examination showed diffuse erythematous lesions on the esophagus and small gastric ulcerations on the antrum of the stomach, and colonoscopic examination also showed multiple punched-out ulcerations and erosions on the entire colon, including the sigmoid colon to the terminal ileum. Diffuse infiltration of CD 3 positive lymphoma cells was found on biopsy. The patient was diagnosed as primary intestinal T-cell lymphoma with diffuse involvement of the entire gastrointestinal tracts from the esophagus to the rectum. Although the patient received systemic combination chemotherapy and achieved partial response initially, the lymphoma relapsed repeatedly.

Keyword

Intestinal; Lymphoma; T-lymphocytes; Gastrointestinal system; Malabsorption syndromes

MeSH Terms

Case Report
Esophageal Neoplasms/therapy*
Esophageal Neoplasms/pathology
Esophageal Neoplasms/diagnosis
Female
Gastrointestinal Neoplasms/therapy*
Gastrointestinal Neoplasms/pathology
Gastrointestinal Neoplasms/diagnosis
Human
Lymphoma, T-Cell/therapy*
Lymphoma, T-Cell/pathology
Lymphoma, T-Cell/diagnosis
Middle Age