Korean J Radiol.  2003 Sep;4(3):141-145. 10.3348/kjr.2003.4.3.141.

Unruptured Aneurysms with Cranial Nerve Symptoms: Efficacy of Endosaccular Guglielmi Detachable Coil Treatment

• Kim DJ
• Kim DI
• Lee SK
• Kim SY

• KMID: 754016
• DOI: http://doi.org/10.3348/kjr.2003.4.3.141

Abstract

OBJECTIVE
To evaluate the efficacy of endosaccular Guglielmi detachable coil (GDC) treatment of unruptured aneurysms causing cranial nerve (CN) symptoms. MATERIALS AND METHODS: Among a database of 218 patients whose aneurysms were treated using GDC, seven patients met the criteria for unruptured aneurysms presenting with symptoms and signs of CN palsy. Changes in CN symptoms before and after GDC treatment were reviewed. RESULTS: Aneurysms were located in the internal carotid-posterior communicating artery (n=3), the basilar bifurcation (n=1) and the cavernous internal carotid artery (n=3). CN symptoms included ptosis (n=6), mydriasis (n=2), and extraocular muscle (EOM) disorder (CN III: n=4; CN VI: n=3). Overall, improvement or resolution of CN symptoms after treatment was noted in five patients. CN symptoms in cases involving small (< or =10 mm) and intradural aneurysms tended to respond better to GDC treatment. Ptosis was the initial symptom to show improvement, while EOM dysfunction responded least favourably. CONCLUSION: GDC coil packing appears to be an appropriate treatment method for the relief of CN symptoms associated with intracranial aneurysms.

Keyword

Aneurysm, cerebral; Aneurysm, therapy; Nerves, cranial; Arteries, therapeutic embolization

Figure

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  Fig. 1 Incidence of cranial nerve signs according to aneurysm location. Note.-EOM(III): extraocular muscle dysfunction, cranial nerve III, IC-Pcom: internal carotid-posterior communicating artery

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  Fig. 2 Outcome of cranial nerve signs after GDC treatment. Note.-EOM(III): extraocular muscle dysfunction, cranial nerve III

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  Fig. 3 Time taken for improvement of oculomotor cranial nerve signs. Patient totals include only those in whom the time taken for improvement or resolution was definite. Note.-EOM(III): extraocular muscle dysfunction, cranial nerve III

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