Yonsei Med J.  1985 Jun;26(1):35-38. 10.3349/ymj.1985.26.1.35.

Circulating Immune Complexes in Diabetics

• Park JY
• Kim SA
• Kim SJ
• Huh KB
• Kim JD

• KMID: 692989
• DOI: http://doi.org/10.3349/ymj.1985.26.1.35

Abstract

Circulating immune complexes (ClC) were detected by platelet aggregation test (PAT) in 40.0% of 45 diabetics and by polyethylene glycol precipitation-complement consumption test (PEG-CC test) in 30.6% of 36 diabetics as compared to 5% and 10% of 20 normal control subjects for each test. The prevalence of CIC in diabetics was significantly higher than in the normal controls (P < 0.05%). There were no correlations between the presence of ClC detected by PAT and the duration of the disease, insulin treatment, or diabetic complications. Thus multiple factors must contribute to the increase of ClC in diabetics. The role of these various factors needs to be studied.

Keyword

Circulating immune complexes; platelet aggregation test; diabetics

MeSH Terms

Antigen-Antibody Complex/metabolism*
Diabetes Mellitus/complications
Diabetes Mellitus/immunology*
Diabetes Mellitus, Insulin-Dependent/drug therapy
Diabetes Mellitus, Insulin-Dependent/immunology
Diabetes Mellitus, Non-Insulin-Dependent/immunology
Human
Insulin/therapeutic use
Platelet Aggregation
Time Factors