Yonsei Med J.  1970 Jun;11(1):60-66. 10.3349/ymj.1970.11.1.60.

Adenoacanthoma of Pyloric Antrum of the Stomach: Report of a Case

• Lee YB
• Choi IJ

• KMID: 687638
• DOI: http://doi.org/10.3349/ymj.1970.11.1.60

Abstract

In view of rarity and its unsolved histogenesis, a case of adenoacanthoma at the pyloric antrum of the stomach is reported. The patient was a 43 years old Korean male teacher who had onset of symptoms referable to present illness three months prior to the admission, although he had ulcer symptoms 7 years previously and subsequently free from the symptoms during last 4 years following 3 years, anti-ulcer regimen. Histopathologic studies of the stomach revealed a large ulcerated lesion at the pyloric antrum, and it was predominantly a well differentiated squamous cell carcinoma occupying the central and superficial part and surrounded by a narrow rim of adenocarcinoma at the periphery. Multiple regional nodes examinations disclosed metastases of only adenocarcinoma in 5 nodes and no metastasis of squamous element was found. A brief review of the literature and a discussion concerning clinical, histopathologic and especially histogenetic aspects is made. It was interesting to note that all squamous cell nests are surrounded by multi-layers of small indifferent basal type of cells, and it was thought that this might possibly be a supportive evidence of direct stimulation to basal cells to differentiate into squamous element.

MeSH Terms

Adenocarcinoma/pathology*
Adult
Human
Male
Pylorus*
Stomach Neoplasms/pathology*