Ann Dermatol.  2026 Feb;38(1):19-26. 10.5021/ad.25.142.

Association Between Psoriasis Risk and Body Mass Index and Waist Circumference in Diabetes: A Population-Based Cohort Study

• Yoo S
• Han K
• Lee JH

• KMID: 2577455
• DOI: http://doi.org/10.5021/ad.25.142

Abstract

Background
Psoriasis is acknowledged for its association with diabetes and obesity. However, the comprehension of the correlation between obesity and psoriasis risk in individuals with diabetes remains limited.
Objective
We aimed to examine the association of body mass index and waist circumference (WC) with the risk of developing psoriasis in individuals with type 2 diabetes mellitus (T2DM).
Methods
This retrospective cohort study utilized nationwide data for exploratory analysis. A total of 2,480,489 participants, all diagnosed with T2DM, were included.
Results
Over a 6.77±1.69-year follow-up, 71,514 patients (2.88%) were diagnosed with psoriasis. Adjusting for multiple variables, the study revealed a J-shaped pattern association between BMI levels and the hazard ratio (HR) for psoriasis in patients with T2DM. A linear pattern relationship was observed regarding WC, with the highest WC group showing the most elevated HR (HR, 1.123; 95% confidence interval, 1.091–1.156).
Conclusion
Understanding the relationship between psoriasis risk and obesity in diabetic individuals holds the potential to enhance the management of patients with T2DM.

Keyword

Body mass index; Diabetes mellitus; Obesity; Psoriasis; Waist circumference