J Pathol Transl Med.
2025 Nov;59(6):467-471. 10.4132/jptm.2025.08.28.
Primary thyroid diffuse large B-cell lymphoma: fine needle aspiration and histological correlation
- Affiliations
-
- 1Department of Pathology, Jeonbuk National University Medical School, Research Institute of Clinical Medicine of Jeonbuk National University, Biomedical Research Institute of Jeonbuk National University Hospital, and Research Institute for Endocrine Sciences, Jeonju, Korea
- 2Department of Otolaryngology, Jeonbuk National University Medical School, Research Institute of Clinical Medicine of Jeonbuk National University, Biomedical Research Institute of Jeonbuk National University Hospital, and Research Institute for Endocrine Sciences, Jeonju, Korea
- KMID: 2573950
- DOI: http://doi.org/10.4132/jptm.2025.08.28
Abstract
- Primary thyroid lymphoma (PTL) is a rare type of cancer that arises within the thyroid gland, representing about 2%–8% of all thyroid malignancies. Fine-needle aspiration cytology is commonly used as the first-line diagnostic approach for thyroid nodules and can assist in identifying PTL when suggestive features are present. Herein, we report the case of a 59-year-old female patient who presented with a rapidly enlarging anterior neck mass over 20 days. Clinically, the case was challenging to distinguish from anaplastic thyroid carcinoma because of the sudden enlargement of the neck mass. However, pathological examination confirmed the diagnosis of primary thyroid diffuse large B-cell lymphoma. Fine-needle aspiration cytology proved valuable in avoiding unnecessary surgical resection and guiding appropriate treatment. Additionally, we provide a brief review of the clinical and cytopathological features of primary thyroid lymphomas.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Fine Needle Aspiration Cytology of Primary Malignant Lymphoma of the Thyroid Gland: A Case Report
- Fine Needle Aspiration Cytologic Findings of Thyroid Lymphoma: Report of Two Cases
- The Primary Thyroid Lymphoma Treated by Surgery without Chemotherapy: Two Cases Reports
- False Negative Fine Needle Aspiration Biopsy Results in Primary Thyroid Lymphoma
- Fine Needle Aspiration Cytology of Primay Malignant Lymphoma of the Breast: A Case Report
