Res Vestib Sci.  2025 Mar;24(1):46-49. 10.21790/rvs.2024.028.

Miller Fisher syndrome initially presented as bilateral internuclear ophthalmoplegia: a case report

Affiliations
  • 1Department of Neurology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea

Abstract

Miller Fisher syndrome can present with various forms of ophthalmoplegia. This case report describes a 57-year-old woman who initially showed bilateral internuclear ophthalmoplegia (INO), with normal imaging and laboratory findings. Her neurologic symptoms progressed to include hyporeflexia and ataxia, leading to a diagnosis of Miller Fisher syndrome. Intravenous immunoglobulin treatment resulted in gradual improvement. This case report highlights the need to consider rare conditions like Miller Fisher syndrome in patients with INO-like features and unclear etiology.

Keyword

Miller Fisher syndrome; Internuclear ophthalmoplegia; Medial longitudinal fasciculus
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