Nerve.  2025 Apr;11(1):21-25. 10.21129/nerve.2025.00710.

Maigne Syndrome and Thoracolumbar Compression Fracture – An Overlooked Combination in Low Back Pain: A Case Report

Affiliations
  • 1Department of Neurosurgery, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Incheon, Republic of Korea

Abstract

Maigne syndrome, also known as thoracolumbar junction syndrome, is an underdiagnosed cause of low back pain that often involves superior cluneal nerve entrapment. This condition can overlap with osteoporotic vertebral compression fractures (OVCFs), complicating the diagnosis. We report two cases of elderly female patients with OVCFs and persistent buttock pain due to cluneal nerve entrapment. Both patients showed significant pain relief after undergoing L1 corpectomy and posterior pedicle screw fixation, with numeric rating scale scores dropping from 8 to 1-3. Early recognition of Maigne syndrome can improve outcomes in patients with atypical pain presentations.

Keyword

Maigne Syndrome; Superior cluneal nerve entrapment; Osteoporotic vertebral compression fracture; Thoracolumbar junction syndrome
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