J Korean Neurol Assoc.  2025 Feb;43(1):50-53. 10.17340/jkna.2024.0060.

Acute Inflammatory Demyelinating Polyradiculoneuropathy in Patient with MOGAD

Affiliations
  • 1Department of Neurology, Jeju National University College of Medicine, Jeju, Korea

Abstract

Antibodies to myelin oligodendrocyte glycoprotein (MOG) are associated with central nervous system demyelination inclusive of optic neuritis and transverse myelitis. MOG antibody may rarely be associated with peripheral nervous system involvement. A 48-year-old woman presented with demyelinating polyneuropathy. She previously suffered from myelitis and optic neuritis and had diagnosed with MOG antibody-associated disease (MOGAD). Polyneuropathies, combined central and inflammatory neuropathies may be associated with MOGAD and may be immunotherapy responsive. Further studies were needed to elucidate the utility of MOG antibody testing in polyneuropathy.

Keyword

Demyelinating diseases; Myelin-oligodendrocyte glycoprotein; Polyneuropathies
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