Korean Circ J.
2024 Dec;54(12):838-850. 10.4070/kcj.2024.0105.
Nationwide Birth Prevalence of Crucial Congenital Heart Defects From 2014 to 2018 in Korea
- Affiliations
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- 1Department of Pediatrics, College of Medicine, Korea University, Seoul, Korea
- 2Biomedical Research Center, Korea University Guro Hospital, Seoul, Korea
- 3National Evidence-based Healthcare Collaborating Agency, Seoul, Korea
- 4Department of Thoracic and Cardiovascular Surgery, Myoungju Hospital, Yongin, Korea
- 5Department of Pediatrics, Sejong General Hospital, Bucheon, Korea
- KMID: 2563799
- DOI: http://doi.org/10.4070/kcj.2024.0105
Abstract
- Background and Objectives
A comprehensive survey of congenital heart disease (CHD) prevalence has not yet been conducted in South Korea. This study aimed to investigate the prevalence of CHDs in Korean children and lay the foundation for national CHD epidemiology.
Methods
Target patients were infantile crucial CHDs, which include critical CHDs (requiring urgent procedures after birth with common hypoxemic defects) and diverse categorical defects excluding simple shunt defects. Data were obtained from the National Health Insurance Service over a 5-year period (2014–2018). Birth prevalence (new cases per 1,000 live births) of CHDs in Korea was analyzed and compared with that of other countries.
Results
The birth prevalences of right heart obstructive defects (pulmonary valve stenosis and pulmonary atresia), conus anomalies (tetralogy of Fallot and double outlet right ventricle), and total anomalous pulmonary venous return showed significant increases in the East Asian group (P<0.001), whereas those of left heart obstructive defects (coarctation of aorta, aortic stenosis, and hypoplastic left heart syndrome), truncus anomalies (D-transposition of great artery and persistent truncus arteriosus), atrioventricular septal defect, and hypoplastic right heart syndrome were significantly decreased in the East Asian group (P<0.001).
Conclusions
The overall birth prevalence of crucial CHDs in Korea was similar to that of critical CHDs in previous studies from other countries. Some subtypes of right heart obstructive defects, left heart obstructive defects, and conotruncal anomalies showed significant differences between East Asian and Western populations. This study contributes to a foundation for national CHD epidemiology in Korean children.
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