J Biomed Transl Res.  2024 Dec;25(4):169-183. 10.12729/jbtr.2024.25.4.169.

Quarantine procedures for management of infectious diseases in non-human primate

• Bae GS
• Koo BS
• Jeon ES
• Lee WK

• KMID: 2563732
• DOI: http://doi.org/10.12729/jbtr.2024.25.4.169

Abstract

Non-human primates, due to their high genetic similarity to humans, are used as laboratory animals in biotechnology researches. The growing demand has recently led to a shortage of primate resources, which has become a significant issue both domestically and internation-ally. This shortage has been further exacerbated by the COVID-19 pandemic. Consequently, the importance of resource conservation through effective primate management is increas-ing. This requires the establishment of proper quarantine procedures and infectious disease control. Quarantine is an important process that protects not only animal health but also pub- lic health significance. Non-human primate quarantine procedures were organized in order. We compared the differences in quarantine procedures not only in Korea but also in various countries such as the US, EU, and Australia. In addition, the etiology, clinical symptoms, diagnosis, and treatment methods of representative infectious diseases of quarantine concern (tuberculosis, monkeypox, monkey immunodeficiency virus, salmonellosis, and shigellosis) were summarized. A literature review of nonhuman primate quarantine procedures in other countries revealed minimal differences in the basic structure. The quarantine periods were similar around 30 days, but we found some differences in details such as legal requirements, documentation forms, and quarantine authorities. These findings are expected to contribute to the development of strategies for improving methods to prevent the spread of infectious diseases and enhancing quarantine management methods.

Keyword

primates; quarantine; animals, laboratory; primates; communicable diseases