Korean J Intern Med.  2025 Jan;40(1):40-48. 10.3904/kjim.2023.485.

Literature review of non-pharmacological treatment for patients with axial spondyloarthritis

• Yeo J
• Seo MR
• Park JW
• Lee YA
• Lee JH
• Kang EH
• Ji SM
• Baek HJ

• KMID: 2563140
• DOI: http://doi.org/10.3904/kjim.2023.485

Abstract

Axial spondyloarthritis (axSpA) is a chronic inflammatory disorder affecting the sacroiliac joints and axial spine. Along with pharmacotherapy, non-pharmacological interventions for axSpA are crucial and constitute the cornerstone of treatment. Here, we review the evidence for non-pharmacological treatment of axSpA as a basis for the 2023 Korean treatment recommendations for patients with axSpA. The effectiveness of the core non-pharmacological approaches, such as education, smoking cessation, and exercise, has been reaffirmed. High-quality research on surgical treatment is limited. However, total hip replacement is advised in patients with ongoing pain or disability and visible structural damage to the hip on imaging. Urgent spinal intervention should be considered in cases of acute spinal pain with neurological deficiency or concurrent unstable fractures. Evidence for complementary therapies, including spas and acupuncture, remains insufficient.

Keyword

Axial spondyloarthritis; Ankylosing spondylitis; Non-pharmacological treatment