Korean J Blood Transfus.
2024 Dec;35(3):196-199. 10.17945/kjbt.2024.35.3.1 9 6.
Trends in Clinical Application of Platelet-Derived Bioproducts
- Affiliations
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- 1Department of Laboratory Medicine, Dong-A University School of Medicine, Busan, Korea
- 2Dong-A University Hospital Public Cord Blood Bank, Busan, Korea
- 3Department of Laboratory Medicine, Jeonbuk National University Medical School, Jeonju, Korea
- 4Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
- KMID: 2562686
- DOI: http://doi.org/10.17945/kjbt.2024.35.3.1 9 6
Abstract
- Platelets contain various growth factors and cytokines. Platelet-derived bioproducts, such as platelet-rich plasma (PRP), platelet-rich fibrin (PRF), and platelet lysate (PL), have been developed and used in clinical practice. PRP and PRF are mainly derived from autologous blood and are used in orthopedics, ophthalmology, skin ulcer treatment, and oral surgery. PL is attracting attention as a substitute for fetal bovine serum in cultures for cell therapy. Research and development on platelet lysate production should be carried out, and transfusion medicine professionals must be involved in the clinical utilization of platelet-derived bioproducts.
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