J Mult Scler Neuroimmunol.
2023 Jun;14(1):56-58. 10.59578/jmsni.2023.14.1.56.
Vasculitic Neuropathy Associated with Pembrolizumab
- Affiliations
-
- 1Department of Medicine, Yonsei University College of Medicine, Seoul, Korea
- 2Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
- 3Department of Pathology, Yonsei University College of Medicine, Seoul, Korea
- KMID: 2561978
- DOI: http://doi.org/10.59578/jmsni.2023.14.1.56
Abstract
- Immune-related neuromuscular complications due to immune checkpoint inhibitors (ICIs) are widely reported. However, cases involving vasculitic neuropathy (VN) are rare. We report a case of pembrolizumab-associated VN, confirmed by nerve biopsy, presenting as mononeuritis multiplex with erythematous skin lesions. Based on negative serological tests for other causes of vasculitis and temporal relationship with ICI treatment, vasculitis was suspected to be associated with pembrolizumab. VN should be considered in patients with progressive neurological symptoms and skin lesions after receiving ICI therapy.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Non-systemic Vasculitic Neuropathy Presenting as Ascending Paralysis
- A Case of Nonsystemic Vasculitic Neuropathy: Electrophysilogic and Pathologic Findings
- Transient Conduction Block in Vasculitic Neuropathy Caused by Churg-strauss Syndrome: Transient Conduction Block in Vasculitic Neuropathy
- Acute Painful Sensory Neuropathy Diagnosed as Nonsystemic Vasculitic Neuropathy
- Study on Clinical Courses of Vasculitic Neuropathies
