Ann Liver Transplant.  2024 Nov;4(2):124-128. 10.52604/alt.24.0016.

Successful living liver donation from a septuagenarian donor with cardiac diseases

• Baik J
• Kim J
• Lee E
• An S
• Oh N
• Gil E
• Kim G

• KMID: 2561859
• DOI: http://doi.org/10.52604/alt.24.0016

Abstract

We present the case of a 74-year-old female who had a right hepatectomy performed laparoscopically to donate her liver to her a 40-year-old son who had alcoholic liver cirrhosis. She voluntarily cooperated, and thorough medical and psychological evaluations were carried out. The receiver underwent surgery in 296 minutes, while the donor took 158 minutes. With normal liver function, the donor and recipient were released from the hospital on days 10 and 14, respectively, after a smooth recovery. Three months following the living donor liver transplant, both the receiver and the living liver donor have not experienced any problems and are doing well.

Keyword

Living donors; Aged; Frail elderly; Atrial fibrillation; Graft survival

Figure

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  Figure 1 Liver images. (A) Explant liver, (B) liver graft in a bench procedure, and (C) implanted liver graft in the recipient.

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  Figure 2 Laboratory changes in living liver donor after donor hepatectomy. (A) Platelet, (B) AST, (C) ALT, and (D) total bilirubin. LDLT, living donor liver transplantation; POD, post operative day; AST, aspartate transaminase; ALT, alanine transaminase.

Reference

1. Chang SH. 2023; Safety of living donors in liver transplantation in a low volume center. Ann Liver Transplant. 3:100–103. DOI: 10.52604/alt.23.0018.

2. Choi JY, Kim JH, Kim JM, Kim HJ, Ahn HS, Joh JW. 2022; Outcomes of living liver donors are worse than those of matched healthy controls. J Hepatol. 76:628–638. DOI: 10.1016/j.jhep.2021.10.031. PMID: 34785324.

3. Kim JM, Joo DJ, Hong SK, You YK, Hwang S, Ryu JH, et al. 2023; Outcomes of sexagenarian living liver donors in Korea: a multicenter study. Liver Transpl. 29:698–710. DOI: 10.1097/LVT.0000000000000104. PMID: 36825584.

4. Toshima T, Rhu J, Yoon YI, Ito T, Uchida H, Hong SK, et al. 2024; Aborted living-donor liver transplantation in the real-world setting, lessons from 13 937 cases of Vanguard Multi-center Study of International Living Donor Liver Transplantation Group. Am J Transplant. 24:57–69. DOI: 10.1016/j.ajt.2023.07.011. PMID: 37517556.

5. Hong SK, Kim M, Kim Y, Kim J, Choi HH, Lee J, et al. 2023; Outcomes of pure laparoscopic donor hepatectomy for a right lobe graft weighing more than 1,000 g. Ann Liver Transplant. 3:11–16. DOI: 10.52604/alt.23.0010.

6. Rhu J, Choi GS, Kim JM, Kwon CHD, Joh JW. 2022; Complete transition from open surgery to laparoscopy: 8-year experience with more than 500 laparoscopic living donor hepatectomies. Liver Transpl. 28:1158–1172. DOI: 10.1002/lt.26429. PMID: 35138684.

7. Rhu J, Choi GS, Kim JM, Kwon CHD, Joh JW. 2023; Risk factors associated with surgical morbidities of laparoscopic living liver donors. Ann Surg. 278:96–102. DOI: 10.1097/SLA.0000000000005851. PMID: 36994737.

8. Chung YK, Park CS, Kang SH. 2022; Association between institutional liver transplantation cases volume and mortality: a meta-analysis of Korea-nationwide cohort studies using Korean National Healthcare Insurance Service database. Ann Liver Transplant. 2:8–14. DOI: 10.52604/alt.22.0011.