J Korean Soc Radiol.  2024 Nov;85(6):1189-1193. 10.3348/jksr.2024.0083.

Clear Cell Sarcoma of the Soft Tissue in the Distal Phalanx of the Great Toe: A Case Report

Affiliations
  • 1Departments of Radiology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea
  • 2Departments of Pathology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea

Abstract

Clear cell sarcoma (CCS) is a rare malignant soft tissue tumor originating from neural crest cells. Histologically resembling malignant melanoma but lacking cutaneous precursor lesions, CCS is characterized by a specific chromosomal translocation (t[12;22][q13;q12]). Primarily affecting young adults, this tumor typically arises in the extremities, especially the knee, foot, and ankle. To our knowledge, distal toe involvement is uncommon. Herein, we present a case initially diagnosed on magnetic resonance imaging as a superficial soft tissue tumor resembling malignant melanoma but subsequently confirmed as CCS of the great toe.

Keyword

Sarcoma; Clear Cell; Soft Tissue Neoplasm; Toes; Magnetic Resonance Imaging
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