Korean J Dermatol.  2024 Nov;62(9):523-526.

A Case of Dermatomyositis Associated with Esophageal Cancer

Affiliations
  • 1Department of Dermatology, Pusan National University School of Medicine, Busan, Korea
  • 2Department of Dermatology, Pusan National University Hospital, Busan, Korea
  • 3Biomedical Research Institute, Pusan National University Hospital, Busan, Korea
  • 4Department of Dermatology, Pusan National University Yangsan Hospital, Yangsan, Korea

Abstract

Dermatomyositis (DM) is a rare systemic autoimmune disorder characterized by distinct skin rash and muscle weakness. Approximately 15%∼30% DM cases present as a paraneoplastic syndrome often associated with an underlying malignancy. Herein, we report the case of a 60-year-old male recently diagnosed with esophageal cancer and exhibited symptoms of DM. The patient presented with generalized muscle weakness and a characteristic skin rash persisting for 3 months. Muscle weakness initially manifested in the proximal arms and later progressed to the proximal legs. In addition, the patient experienced difficulty in swallowing food. Clinical, laboratory, histological, and imaging assessments confirmed the diagnosis of DM associated with esophageal cancer. Notably, both DM and esophageal cancer can cause dysphagia. Therefore, accurate differentiation of dysphagia resulting from malignancy from that resulting from DM is pivotal in the diagnostic process.

Keyword

Deglutition disorders; Dermatomyositis; Esophageal neoplasms
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