Brain Tumor Res Treat.
2024 Oct;12(4):230-236. 10.14791/btrt.2024.0030.
Clinical Experiences Using CyberKnife for Large-Volume Meningiomas: A Preliminary Study
- Affiliations
-
- 1Department of Neurosurgery, Gyeongsang National University Changwon Hospital, Changwon, Korea
- 2Department of Neurosurgery, College of Medicine, Gyeongsang National University, Jinju, Korea
- KMID: 2561287
- DOI: http://doi.org/10.14791/btrt.2024.0030
Abstract
- Background
This preliminary study evaluates the safety and efficacy of CyberKnife radiosurgery (CKRS) for large-volume meningiomas (≥10 cm3 ), where surgical options may be limited due to tumor location or patient health conditions.
Methods
We retrospectively analyzed 18 patients with meningiomas treated with CKRS at Gyeongsang National University Hospital between 2010 and 2020. Tumor control and survival rates were evaluated, with follow-up imaging performed regularly.
Results
CKRS achieved a 5-year overall survival rate of 92.3% and a 5-year tumor control rate of 93.8%. Symptomatic peritumoral edema occurred in 61.1% of patients, with 16.7% requiring surgical intervention.
Conclusion
CKRS appears to be a promising option for patients with large meningiomas, show- ing good tumor control and manageable complications. Further studies with larger cohorts are necessary to confirm these findings.
