J Cardiovasc Interv.
2024 Apr;3(2):52-61. 10.54912/jci.2023.0020.
Post-Infarction Ventricular Septal Rupture: Pathophysiology, Clinical Presentation, Diagnosis, and Treatment
- Affiliations
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- 1Cardiology, Cardiovascular Center, Pusan National University Yangsan Hospital, Yangsan, Korea
- 2Department of Internal Medicine, Kyungpook National University Hospital, Daegu, Korea
- 3Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea
- 4Department of Internal Medicine, Pusan National University School of Medicine, Yangsan, Korea
- KMID: 2560960
- DOI: http://doi.org/10.54912/jci.2023.0020
Abstract
- A ventricular septal defect (VSD) following an acute myocardial infarction (MI) is a devastating mechanical complication. While the incidence of post-MI VSD has decreased significantly with the advancement of early reperfusion therapy such as primary percutaneous coronary interventions, the clinical outcomes of post-MI VSD remain challenging. Moreover, determining the timing and approach to treatment is very complicated. This article reviews the pathophysiology, clinical presentation, diagnosis, and treatment of post-MI VSD, including percutaneous defect closure.
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