Investig Clin Urol.
2024 Nov;65(6):587-592. 10.4111/icu.20240280.
Analysis of sleep pattern in patients with nocturnal enuresis: A prospective, observational, pilot study
- Affiliations
-
- 1Department of Urology, Kyung Hee University Hospital at Gangdong, Kyung Hee University College of Medicine, Seoul, Korea
- 2Department of Urology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea
- 3Basic-Clinic Convergence Research Institute, University of Ulsan, Ulsan, Korea
- KMID: 2560752
- DOI: http://doi.org/10.4111/icu.20240280
Abstract
- Purpose
This study aimed to analyze the sleep patterns of patients with nocturnal enuresis (NE) using a wearable brain-wave-sensing device.
Materials and Methods
We prospectively analyzed 10 of the 14 patients who visited the hospital for NE between August 2023 and July 2024 and agreed to participate in the study. Four patients were excluded owing to pairing errors and loss to follow-up. Participants were instructed to maintain a frequency volume chart for 1 week and sleep while wearing MUSE-STM , a wearable brainwave detection device. We monitored the arousal threshold state based on sleep patterns when NE occurred in all patients.
Results
The median age of the patients was 8.7 years (interquartile range, 7.0–10.6), and 4 patients (40.0%) were male. In all participants, non-rapid eye movement (NREM) deep sleep was the dominant stage in the early part of sleep, whereas NREM light sleep was dominant in the middle part. The arousal threshold was high in the early part of sleep and decreased toward the end. A poor response to enuretic alarms was observed when NE occurred during the NREM deep-dominant period. In contrast, a good response was observed when NE occurred during the NREM light-dominant period.
Conclusions
Differences in sleep stages influence the arousal threshold more than individual characteristics. To effectively manage the NE, focusing on the timing of urination is important in the latter part of the sleep period.
