J Breast Cancer.
2024 Aug;27(4):235-247. 10.4048/jbc.2023.0234.
Intensive Surveillance for Women With Breast Cancer: A Multicenter Retrospective Study in Korea
- Affiliations
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- 1Department of Surgery, Chungbuk National University Hospital, College of Medicine, Chungbuk National University, Cheongju, Korea
- 2Department of Surgery, Seoul National University College of Medicine, Seoul, Korea
- 3Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
- 4Department of Surgery, Kosin University Gospel Hospital, Busan, Korea
- 5Department of Surgery, Soonchunhyang University Bucheon Hospital, Bucheon, Korea
- 6Department of Surgery, National Cancer Center, Goyang, Korea
- 7Department of Surgery, Soonchunhyang University Seoul Hospital, Seoul, Korea
- 8Department of Surgery, Samsung Seoul Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
- 9Department of Surgery, Korea University Anam Hospital, Seoul, Korea
- 10Department of Surgery, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea
- 11Department of Surgery, Research Institute of Clinical Medicine of Jeonbuk National University, Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Korea
- KMID: 2559273
- DOI: http://doi.org/10.4048/jbc.2023.0234
Abstract
- Purpose
This study evaluated the effectiveness of different surveillance intensities on morbidity and mortality in women with breast cancer.
Methods
This retrospective study included patients who had undergone breast cancer surgery in the Republic of Korea between 2009 and 2011. The patients were divided into two groups based on the intensity of their postsurgical surveillance: intensive surveillance group (ISG) and less-intensive surveillance group. Surveillance intensity was measured based on the frequency and type of follow-up diagnostic tests conducted, including mammography, ultrasonography, computed tomography, magnetic resonance imaging, bone scans, and positron emission tomography scans.
Results
We included 1,356 patients with a median follow-up period of 121.2 months (range, 12.8–168.0 months). The analysis revealed no significant difference in the overall survival (OS) between the two groups within five years of surgery. However, patients with ISG exhibited significantly better breast cancer-specific survival (BCSS) and distant metastasisfree survival (DMFS) within the same period. Five years after surgery, the differences in survival outcomes between the groups were not statistically significant.
Conclusion
Intensive surveillance did not demonstrate a significant improvement in OS for patients with breast cancer beyond five years postoperatively. However, within the first five years, intensive surveillance was associated with better BCSS and DMFS. These findings suggest that personalized surveillance strategies may benefit specific patient subsets, particularly in the early years after treatment. Further nationwide randomized studies are warranted to refine surveillance guidelines and optimize outcomes in patients with breast cancer.
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