Psychiatry Investig.  2024 Sep;21(9):958-970. 10.30773/pi.2024.0066.

Neurocognitive Characteristics of Patients Who Visited a Psychiatric Outpatient Clinic Requesting Treatment for Adult Attention-Deficit/Hyperactivity Disorder

Affiliations
  • 1Department of Neuropsychiatry, Seoul National University Hospital, Seoul, Republic of Korea
  • 2Department of Human Systems Medicine, Seoul National University, Seoul, Republic of Korea
  • 3Department of Psychiatry, National Traffic Injury Rehabilitation Hospital, Yangpyeong, Republic of Korea
  • 4Department of Psychiatry, Seoul National University College of Medicine, Seoul, Republic of Korea
  • 5Clinical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea

Abstract


Objective
This study investigated the neurocognitive characteristics of patients who visited an outpatient clinic requesting diagnosis and treatment for adult attention-deficit/hyperactivity disorder (ADHD).
Methods
The patients’ electronic medical records were retrospectively reviewed. Neurocognitive test results were compared using Student’s t-test according to their chief complaint, depressive symptoms, childhood history, and intelligence quotient (IQ). Neurocognitive characteristics affecting subjective symptoms of ADHD were analyzed by linear regression.
Results
The study included 106 patients. They did not have significant deficits in neurocognitive tests. Patients with depressive symptoms showed more impulsive responses (hit reaction time [p=0.037] and commission error [p=0.024]) and self-reported ADHD symptoms (p=0.001). Verbal (p=0.036) and visual memory (p=0.020) were significantly deficient in patients with a childhood ADHD diagnosis. Patients with a low IQ had significant deficits in various domains. Depressive symptoms and vigilance were significantly related to subjective symptoms of ADHD (adjusted R2=0.430, β=0.457, p=0.002).
Conclusion
Our results imply that the neurocognitive function of patients with subjective ADHD symptoms was not abnormal but was affected by depressive symptoms.

Keyword

Adult; Attention-deficit hyperactivity disorder; Neurocognitive test; Self-report questionnaire; Mood disorder
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