Korean J Dermatol.  2024 Jul;62(6):358-361.

Extensive Kaposi’s Varicelliform Eruption with Sepsis in Patients with Atopic Dermatitis

• Lee J
• Lee G
• Shin JO
• Roh DY
• Kim Y
• Won SH
• Shin K
• Kim H
• Ko H
• Kim BS
• Kim MB
• Lee J

Abstract

Kaposi’s varicelliform eruption (KVE) is a rare viral infection primarily caused by herpes simplex virus (HSV). This condition frequently presents concomitantly with underlying chronic skin disorders, particularly atopic dermatitis (AD). This report describes a rare case of sepsis resulting from KVE in a patient with AD. A 30-year-old male patient with a history of AD presented with painful skin lesions characterized by papulovesicular eruptions, crusts, erythema, and erosions, initially localized to the neck and spreading throughout his body, accompanied by a high fever. Laboratory findings confirmed HSV infection and sepsis. Thus, a diagnosis of KVE compounded by sepsis was established. Systemic acyclovir and antibiotics led to complete recovery within 3 weeks, with resolution of fever and skin manifestations, and general health improvement. Timely recognition and management of KVE are crucial for prevention of adverse outcomes. Both physicians and patients with AD should be made aware of the predisposing factors and risks associated with KVE.

Keyword

Atopic dermatitis; Kaposi varicelliform eruption; Sepsis