J Periodontal Implant Sci.  2022 Apr;52(2):116-126. 10.5051/jpis.2102080104.

Applying nano-HA in addition to scaling and root planing increases clinical attachment gain

• Uysal
• Ustaoğlu G
• Behçet M
• Albayrak
• Tunalı M

• KMID: 2557786
• DOI: http://doi.org/10.5051/jpis.2102080104

Abstract

Purpose
This study evaluated the efficacy of treating periodontitis using subgingival nanohydroxyapatite powder with an air abrasion device (NHAPA) combined with scaling and root planing (SRP).
Methods
A total of 28 patients with stage III periodontitis (grade B) were included in this study, although 1 was lost during follow-up and 3 used antibiotics. The patients were divided into a test group and a control group. All patients first received whole-mouth SRP using hand instruments, and a split-mouth approach was used for the second treatment. In the test group, the teeth were treated with NHAPA for 15 seconds at 70% power per pocket. Subgingival plaque samples were obtained from the 2 deepest pockets at the test and control sites before treatment (baseline) and 3 months after treatment. The full-mouth plaque index (PI), gingival index (GI), papillary bleeding index (PBI), bleeding on probing (BOP), probing depth (PD) and clinical attachment level (CAL) were recorded at baseline and at 1- and 3-month post-treatment. Real-time polymerase chain reaction was used to determine the colonisation of Treponema denticola (Td), Porphyromonas gingivalis (Pg), and Aggregatibacter actinomycetemcomitans in the subgingival plaque.
Results
From baseline to the first month, the test group showed significantly larger changes in BOP and CAL (43.705%±27.495% and 1.160±0.747 mm, respectively) than the control group (36.311%±27.599% and 0.947±0.635 mm, respectively). Periodontal parameters had improved in both groups at 3 months. The reductions of PI, GI, BOP, PD, and CAL in the test group at 3 months were greater and statistically significant. The total bacterial count and Td and Pg species had decreased significantly by the third month in both groups (P<0.05).
Conclusions
Applying NHAPA in addition to SRP improves clinical periodontal parameters more than SRP alone. Subgingival NHAPA may encourage clot adhesion to tooth surfaces by increasing surface wettability.

Keyword

Anaerobic bacteria; Hydroxyapatites; Periodontal debridement; Periodontitis; Real-time polymerase chain reaction