Infect Chemother.  2024 Jun;56(2):204-212. 10.3947/ic.2022.0167.

Risk of Severe Acute Respiratory Syndrome Coronavirus 2 Transmission in Seoul, Korea

Affiliations
  • 1Seoul Metropolitan Government, Seoul, Korea
  • 2Department of Pharmacology, University of Ulsan College of Medicine, Seoul, Korea
  • 3Department of Otorhinolaryngology, Asan Medical Center and College of Medicine, University of Ulsan, Seoul, Korea
  • 4Lablup Inc., Seoul, Korea
  • 5Allergy Immunology Center, Korea University, Seoul, Korea
  • 6Department of Pediatrics, Korea University Anam Hospital and Korea University College of Medicine, Seoul, Korea

Abstract

Background
The risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission during the endemic phase may vary from that during the previous pandemic phase. We evaluated the risk of infection in a general population with laboratory-confirmed coronavirus disease 2019 (COVID-19) in a community setting in Korea.
Materials and Methods
This study included 1,286 individuals who had been in contact with an index COVID-19 case between January 24, 2020, and June 30, 2022. Variables such as age, sex, nationality, place of contact, level of contact, the status of exposed cases, period, and level of mask-wearing were assessed.
Results
Among 1,286 participants, 132 (10.30%) were confirmed to have COVID-19. With increasing age, the risk of the exposed persons contracting COVID-19 from index cases tended to increase (P <0.001), especially for people in their 70s (odds ratio, 1.24; 95% confidence interval, 1.11–1.40; P <0.001). We found an increasing trend in the risk of a COVID-19 exposed case becoming a secondary infection case (P <0.001) in long-term care facilities where the attack rate was high.
Conclusion
The risk of COVID-19 transmission is high in long-term care facilities where many older adults reside. Intensive management of facilities at risk of infection and strict mask-wearing of confirmed COVID-19 cases are necessary to prevent the risk of COVID-19 infection.

Keyword

COVID-19; Contact tracing; Physical distancing; Masks
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