Korean J Dermatol.  2024 Jun;62(5):306-309.

Cutaneous Collagenous Vasculopathy in a 23-Year-Old Male: A Case Report

Affiliations
  • 1Departments of Dermatology, Yeungnam University College of Medicine, Daegu, Korea
  • 2Departments of Pathology, Yeungnam University College of Medicine, Daegu, Korea

Abstract

Cutaneous collagenous vasculopathy (CCV) was first suggested by Salama and Rosenthal in 2000. CCV is characterized by blanching erythematous macules with telangiectasia, which begins on both lower legs and spreads to the trunk and upper extremities. A 23-year-old male visited our clinic presenting with diffuse blanching and confluent erythematous patches with telangiectasia on both lower legs and thighs with a burning sensation. The skin lesions had progressed in a spreading pattern 5 years ago. On histopathologic examination, dilated blood vessels with thick walls and perivascular amorphous material were observed in the superficial dermis. Furthermore, the basement membrane of the dilated blood vessels was positive for periodic acid-Schiff stain and collagen type IV immunohistochemical staining. Based on these clinicopathologic features, we diagnosed CCV. Herein, we report an interesting case of CCV, which is the first report in Korea.

Keyword

Collagenous; Microangiopathy; Vasculopathy
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