J Wound Manag Res.
2024 Jun;20(2):170-177. 10.22467/jwmr.2024.02936.
Hyperbaric Oxygen Therapy and Prostaglandin E on Composite Graft for Fingertip Amputation: Two Case Reports
- Affiliations
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- 1Department of Plastic and Reconstructive Surgery, Wonkwang University Hospital, Iksan, Korea
- KMID: 2557005
- DOI: http://doi.org/10.22467/jwmr.2024.02936
Abstract
- Fingertip amputation is a common traumatic injury which can be treated with revascularization therapy or composite grafting. This article reports two case studies showing the successful management of fingertip amputation using hyperbaric oxygen therapy (HBOT) and prostaglandin E1 (PGE1) treatment after composite grafting, where revascularization was not possible. HBOT was used to promote angiogenesis, improve oxygen transfer, and accelerate wound healing. At the same time, PGE1 was administered to control inflammation, stimulate cell proliferation, and promote tissue repair. These case reports offer effective approaches to treating fingertip amputation. The treatment strategy used in this study can be expected to improve patient outcomes and quality of life.
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