Korean J Intern Med.  2024 Jul;39(4):563-576. 10.3904/kjim.2023.487.

Approaches and considerations in the endoscopic treatment of T1 colorectal cancer

• Jung Y

• KMID: 2556907
• DOI: http://doi.org/10.3904/kjim.2023.487

Abstract

The detection of early colorectal cancer (CRC) is increasing through the implementation of screening programs. This increased detection enhances the likelihood of minimally invasive surgery and significantly lowers the risk of recurrence, thereby improving patient survival and reducing mortality rates. T1 CRC, the earliest stage, is treated endoscopically in cases with a low risk of lymph node metastasis (LNM). The advantages of endoscopic treatment compared with surgery include minimal invasiveness and limited tissue disruption, which reduce morbidity and mortality, preserve bowel function to avoid colectomy, accelerate recovery, and improve cost-effectiveness. However, T1 CRC has a risk of LNM. Thus, selection of the appropriate treatment between endoscopic treatment and surgery, while avoiding overtreatment, is challenging considering the potential for complete resection, LNM, and recurrence risk.

Keyword

Colonic neoplasms; Endoscopic mucosal resection; Colorectal surgery; Lymphatic metastasis