Korean J Head Neck Oncol.
2024 May;40(1):43-47. 10.21593/kjhno/2024.40.1.43.
A Case of Giant Malignant Peripheral Nerve Sheath Tumor of Neck
- Affiliations
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- 1Department of Otorhinolaryngology-Head & Neck Surgery, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea
- KMID: 2556209
- DOI: http://doi.org/10.21593/kjhno/2024.40.1.43
Abstract
- Malignant peripheral nerve sheath tumor (MPNST) is an extremely rare sarcoma of soft tissue. It is locally invasive, frequently recurred and metastasizes distantly, therefore has a very poor prognosis. the most involved sites are human body and extremities, and MPNST occurs and involved very rarely in the parapharynx of neck. MPNST does not react to radiotherapy and chemotherapy, therefore complete surgical resection is the most important treatment. Since immunohistochemical staining is essential for the final diagnosis, it is common to be confirmed after surgery. We report a case of giant MPNST without symptom in the head and neck involving the right parapharynx with multiple distant metastases in a 74-year-old patient on a review of the literature.
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