Korean J Ophthalmol.  2024 Jun;38(3):194-202. 10.3341/kjo.2023.0129.

Self-Reported Findings of the Korean Intermittent Exotropia Multicenter Study Questionnaire

• Yang HK
• Park SH
• Lee HJ
• Kim SY
• Gye HJ
• Kim SY
• Shin SY
• Lim KH
• the Korean Association of Pediatric Ophthalmology and Strabismus (KAPOS)

• KMID: 2556189
• DOI: http://doi.org/10.3341/kjo.2023.0129

Abstract

Purpose
To determine subjective symptoms and medical history of patients with intermittent exotropia in a large study population.
Methods
The Korean Intermittent Exotropia Multicenter Study (KIEMS) is a nationwide, observational, cross-sectional, multicenter study conducted by the Korean Association for Pediatric Ophthalmology and Strabismus including 5,385 patients with intermittent exotropia. Subjective symptoms and medical history of patients with intermittent exotropia were extracted by a comprehensive survey based on a self-administered questionnaire according to the study protocol of the KIEMS.
Results
The mean age of symptom onset was 5.5 years. The most common symptom reported in patients with intermittent exotropia was photophobia (52.1%), followed by diplopia at near fixation (7.3%) and distance fixation (6.2%). Preterm birth was found in 8.8%, and 4.1% had perinatal complications. A family history of strabismus was present in 14.9%, and 5.5% of patients had a family member who underwent strabismus surgery.
Conclusions
The KIEMS is one of the largest clinical studies on intermittent exotropia. Intermittent exotropia frequently caused photophobia and diplopia, and patients with a family history was not uncommon.

Keyword

Exotropia; Multicenter study; Surveys and questionnaires; Symptoms