Clin Transplant Res.  2024 Mar;38(1):18-22. 10.4285/kjt.23.0062.

Patient management for thoracic organ donor candidates: the lung transplantation team’s view

Affiliations
  • 1Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea
  • 2Transplantation Research Center and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Korea

Abstract

Despite the increasing demand for lung transplants, donor lungs remain in short supply. Although organ donations have been steadily increasing in Korea, with the utilization rate for donor lungs increasing to 40% in recent years, many potential donor organs remain unused. To match the increasing number of patients on the lung transplant waitlist, it is essential to increase the donor procurement rate through optimal management. Improvements in donor lung management programs can lead to expansion of the donor pool and optimal posttransplant outcomes. This review focuses on basic protocols for the optimal management of donor lungs and summarizes coronavirus disease 2019-related considerations for donor lung evaluation.

Keyword

Lung transplantation; Donors; Management

Figure

  • Fig. 1 Donor heart and lung management algorithm. ECG, electrocardiogram; CXR, chest X-ray; ABG, arterial blood gas; AFB's, acid fast fluorescent stain; CVP, central venous pressure; MAP, mean arterial pressure; TV, tidal volume; PEEP, positive-end expiratory pressure; IV, intravenous; BGL, blood glucose level; Echo, echocardiogram; T3, tri-iodothyronine; T4, thyroxine; LV, left ventricle; LVEF, left ventricular ejection fraction. Reproduced from Copeland et al. [8] with permission of Elsevier according to the Creative Commons license.


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