J Dig Cancer Res.  2024 Apr;12(1):1-5. 10.52927/jdcr.2024.12.1.1.

Factors Associated with Gastric and Duodenal Neuroendocrine Tumor Development

Affiliations
  • 1Department of Gastroenterology, Dankook University Hospital, Dankook University College of Medicine, Cheonan, Korea
  • 2Department of Internal Medicine, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu, Korea

Abstract

The incidence and prevalence of upper gastrointestinal neuroendocrine tumors (NETs), including gastric NETs (GNETs) and duodenal NETs (DNETs), have been gradually increasing. These trends may be associated with the increased use of health checkups, which includes upper endoscopy, in conjunction with better disease recognition. However, the clinical factors associated with GNETs and DNETs remain unknown; previous studies revealed discrepancies. Recently, metabolic disorders have been indicated as potential factors that are associated with GNETs and DNETs. This review summarizes the results of previous studies and briefly introduces the results of a recent Korean multicenter study on the factors associated with GNETs and DNETs.

Keyword

Neuroendocrine tumors; Stomach; Duodenum; Associated factors
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