Pediatr Infect Vaccine.  2024 Apr;31(1):64-74. 10.14776/piv.2024.31.e3.

Hospital-Acquired Measles: A Systematic Review Using the Outbreak Reports and Intervention Studies of Nosocomial Infection (ORION) Statement

• Bolormaa E
• Kang CR
• Kim HH
• Choe YJ

• KMID: 2555427
• DOI: http://doi.org/10.14776/piv.2024.31.e3

Abstract

Purpose
Despite the recent increased number of nosocomial measles, the outbreak investigation reports are not usually standardized, thus posing unclear understanding of magnitude of its public health burden. We used the Outbreak Reports and Intervention Studies of Nosocomial Infection (ORION) statement, to compare nosocomial outbreaks and synthesize evidence to prevent hospital transmission of measles.
Methods
A PubMed, Web of Science, Embase, Scopus, and Cochrane search in English, using the medical subject headings “measles,” “nosocomial,” “hospital,” and “healthcare,” was performed. We evaluated the quality of outbreak reports of nosocomial measles infection worldwide using the ORION statement findings and recommendations.
Results
We reviewed 24 studies in accordance to the ORION statement. Measles transmission in healthcare settings is a significant burden on the morbidity, mortality, and economy of measles. The healthcare workers’ booster vaccination guidelines should be monitored and enhanced during the post-elimination period of measles. The outcomes of infections must be explicit for outbreak reports.
Conclusions
This study identified the epidemiological and clinical characteristics of nosocomial measles infections and provided strong evidence for infection control policies in hospitals.

Keyword

Measles; Healthcare; Hospital