Clin Ultrasound.  2016 Nov;1(2):78-83. 10.18525/cu.2016.1.2.78.

Ultrasonographic and Clinical Characteristics of the Solid Varient of Papillary Thyroid Carcinoma

• Kim BK
• Lee SJ
• Ok SY
• Kwon SK
• Choi YS

• KMID: 2555383
• DOI: http://doi.org/10.18525/cu.2016.1.2.78

Abstract

Background/Aims
The solid variant of papillary thyroid carcinoma (SVPTC) is one of rarest subtype of papillary thyroid carcinoma. There are few studies of the clinical and ulrasonographic (US) features of SVPTC. The aim of this study was to evaluate the clinical and ultrasonographic features of patients with 17 SVPTC treated at our institution.
Methods
Of the 4,136 patients with PTC who were underwent thyroidectomy at our institution between January 2009 and September 2013, 17 patients with SVPTC were retrospectively reviewed.
Results
Of those 17 patients with SVPTC, two (11.7%) were men and 15 (88.3%) were women, with a mean age of 49.2 years (range: 19- 71 years). The mean tumor size was 1.4 ± 0.6 cm (range: 0.5-3.2 cm). The lymph node metastases were observed in 10 patients (58.9%). The extrathyroidal invasions were found in twelve (70.6%). The mean follow-up period was 33.5 months (range: 6-67 months). No patient experienced tumour recurrence or distant metastasis during follow-up. On US, the majority of nodules had irregular (8 [47.1%]) or taller than wide (6 [35.3%]) shapes with solid (16 [94.1%]). The margin of nodules was ill-defined or spiculate margins (16 [94.1%]). The echogenecity of nodules was hypoechoic (7 [41.2%]) or markedly hypoechoic (9 [52.9%]). The microcalcification was seen in seven (41.1%).
Conclusions
The SVPTC is not associated with distant metastasis and poor prognosis as previously thought. The SVPTC tends to have relatively malignant sonographic features such as taller than wide shape, markedly hypoechoic, spiculated margin and microcalcifications.

Keyword

갑상선 유두암; 고형 변이성; 초음파; Thyroid cancer, Papillar; Solid variant; Ultrasonography