Clin Ultrasound.  2017 Nov;2(2):53-59. 10.18525/cu.2017.2.2.53.

The Diagnostic Value of Core Needle Biopsy in Sonographically Suspicious Thyroid Nodules with Benign and Atypia of Undetermined Significance Cytologic Results

Affiliations
  • 1Department of Nuclear Medicine, Jeju National University School of Medicine, Jeju, Korea
  • 2Department of Radiology, Kosin University College of Medicine, Busan, Korea
  • 3Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea

Abstract

Background/Aims
Core needle biopsy (CNB) has been recently described as an accurate second-line test in thyroid inconclusive fine needle aspiration (FNA) cytology. The purpose of this study was to investigate the diagnostic value of CNB in sonographically suspicious thyroid nodules with initially benign and atypia of undetermined significance (AUS) cytologic results.
Methods
From June 2015 through March 2017, 94 patients were underwent ultrasound (US) guided CNB for initially benign and AUS cytologic results with suspicious US features were included.
Results
Of those 94 cases, 24 cases (25.5%) underwent repeated FNA more two times. 11 cases (28.9%) of 38 cases of benign cytology and 29 cases (51.8%) of 56 AUS cases were diagnosed papillary thyroid carcinoma (PTC) by CNB. Among the 40 cases diagnosed PTC by CNB, 21 cases were operated and confirmed PTC.
Conclusion
In conclusion, CNB is clinically useful in managing thyroid nodules with suspicious US features after an initial benign and AUS cytologic results.

Keyword

갑상선 결절; 초음파; 중심부바늘생검; 세침흡인생검; Thyroid nodule; Ultrasonography; Core needle biopsy; Fine needle aspiration biopsy
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