Clin Ultrasound.  2018 May;3(1):28-31. 10.18525/cu.2018.3.1.28.

Gallbladder Squamous Cell Carcinoma with Chronic Right Upper Quadrant Discomfort

Affiliations
  • 1Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea
  • 2Department of Surgery, Wonkwang University Sanbon Hospital, Gunpo, Korea
  • 3Department of Radiology, Wonkwang University Sanbon Hospital, Gunpo, Korea
  • 4Department of Internal Medicine and Wonkwang Digestive Disease Research Institute, Wonkwang University Sanbon Hospital, Gunpo, Korea

Abstract

A 74-year-old female patient was referred to our hospital with a one-month history of right upper abdominal discomfort and general weakness. Transabdominal ultrasonography conducted by a private clinic showed irregular wall thickening of the gallbladder and protruding mass into the gallbladder lumen. Computed tomography and magnetic resonance image in Wonkwang University Sanbon Hospital suggested gallbladder cancer or xanthogranulomatous cholecystitis. Extended cholecystectomy was performed. The finding of operation revealed gallbladder squamous cell carcinoma with mucosal destruction, emphysematous change of gallbladder and multiple gallbladder stones. Cancer invaded transverse colon, common bile duct, and hepatic artery. After the operation, the patient improved clinically, and is scheduled to treat adjuvant chemotherapy. The squamous cell carcinoma of the gallbladder is a rare histopathologic subtype of gallbladder cancer and has a highly proliferative character. Due to aggressive behavior, early detection and curative resection play an important role in survival benefit.

Keyword

담낭암; 편평상피세포암; 초음파; 전산화단층촬영술; Gallbladder cancer; Carcinoma, Squamous cell; Ultrasonography; Multidetector computed tomography
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