Clin Ultrasound.  2018 Nov;3(2):56-61. 10.18525/cu.2018.3.2.56.

The Comparison of Vibration-Controlled Transient Elastography and 2D-Shear Wave Elastography in Chronic Liver Disease

• Heo J
• Baik SK
• Kim MY

• KMID: 2555354
• DOI: http://doi.org/10.18525/cu.2018.3.2.56

Abstract

Background/Aims
The evaluation of liver fibrosis is important in the management of chronic liver disease. Because of limitations of liver biopsy in clinical use, ultrasound base elastographies to estimate liver stiffness have been developed. We investigated the correlation and consistency between the vibration-controlled transient elastography (VCTE) and 2-dimensional swear wave elastography (2D-SWE).
Methods
For 161 patients with chronic liver disease, VCTE and 2D-SWE were measured simultaneously. In addition, serologic fibrosis markers Fib-4 and APRI were also estimated. The correlation between each other markers were analyzed.
Results
VCTE showed good correlation with serologic fibrosis marker Fib-4 (r = 0.359, p < 0.001) and APRI (r = 0.333, p < 0.001). 2D-SWE also showed good correlation with Fib-4 (r = 0.277, p < 0.001) and APRI (r = 0.250, p < 0.001). There was also good correlation between VCTE and 2D-SWE (r = 0.895, p < 0.001). The failure in examination was only observed in VCTE (9.9%) and the most common cause was obesity. Conclusion: VCTE and 2D-SWE both showed good correlation with each other and with serologic fibrosis markers. However, 2D-SWE showed better performance in clinical practice.

Keyword

Vibration-controlled transient elastography (VCTE); 2-dimensional swear wave elastography (2D-SWE); 간섬유화; 만성 간질환; Vibration-controlled transient elastography; 2-dimensional swear wave elastography; Fibrosis; Chronic liver diseases