J Neurointensive Care.  2020 Oct;3(2):29-32. 10.32587/jnic.2020.00311.

Current Prophylactic Hypothermia for Intracranial Hypertension after Traumatic Brain Injury

Affiliations
  • 1Department of Neurosurgery, Korea University Medical Center, Anam Hospital, Korea University College of Medicine, Seoul, Korea

Abstract

Hypothermia performed in patients with traumatic brain injury (TBI) is used to reduce cerebral metabolism and cerebral blood flow, subsequently reducing intracranial pressure (ICP). There have been many disagreements about the effectiveness of prophylactic hypothermia in its clinical application. Until now, hypothermia has been used without standardized treatment guidelines and performed by each medical provider’s personal judgement. Recently, a large-scale randomized controlled trial (RCT) regarding hypothermia was conducted, and it concluded that the early use of therapeutic hypothermia in the staged management of ICP elevation is not beneficial. Therefore, it is our latest knowledge that it is difficult to derive a standardized treatment protocol for prophylactic hypothermia in TBI patients, and also it is not beneficial to the patient.

Keyword

Hypothermia; Traumatic brain injury; Intracranial pressure; Intracranial hypertension
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