Saf Health Work.  2024 Mar;15(1):118-122. 10.1016/j.shaw.2023.11.005.

Biosafety Risk Control Strategies in Laboratory Animal Research

• Weng St
• Li Qw
• Gao Yd
• Qiu Yf

• KMID: 2554320
• DOI: http://doi.org/10.1016/j.shaw.2023.11.005

Abstract

To understand biosafety's current situation in laboratory animal research and risk factors affecting occupational health. Compliance surveys were conducted by questionnaire via Questionnaire Star (an application app on the Internet) in Chinese. Thirty-nine anonymous questionnaires were collected. The surveyed institution has established 24 types of ABSL (Animal Biosafety Laboratory) and biosafety management organizations and systems equipped with safety equipment. Our study also suggests that the principal of the laboratory establishment fails to perform supervision and inspection responsibilities, the inappropriate design of the animal biosafety laboratory, non-standardized personnel training and health management, non-strict waste management, and insufficient emergency management. The administrative department and work units should address certain safety and occupational health risks in laboratory animal research. The author proposes control strategies based on organizational guarantee, personnel management, emergency management, etc., to help prevent risks and ensure occupational health. Due to regional limitations and small sample size, the results may not be generalisable to all parts of the world. However, some of the key common issues may also be present in other regions, so we believe that this research still has some relevance.

Keyword

Animal experiment; Biosafety; Control strategy; Occupational health risk; Practical investigation; Risk assessment