Clin Exp Reprod Med.  2024 Mar;51(1):63-68. 10.5653/cerm.2023.06163.

Effect of prior cesarean delivery on the outcomes of intracytoplasmic sperm injection

• Gewida SA
• Rabbo MSEA
• Samra MAEE
• Moneim HMAA

• KMID: 2553187
• DOI: http://doi.org/10.5653/cerm.2023.06163

Abstract

Objective
This study was conducted to investigate the impact of previous delivery mode on pregnancy outcomes in patients with secondary infertility after frozen-thawed embryo transfer.
Methods
This prospective observational study included 140 patients experiencing secondary infertility. Of these, 70 patients had a previous cesarean delivery (CD), while the remaining 70 patients had a previous normal vaginal delivery (NVD). The primary outcome was the implantation rate. The secondary outcomes included rates of clinical pregnancy, chemical pregnancy, miscarriage, and ectopic pregnancy.
Results
The comparison of all fertility outcomes between the two groups revealed no statistically significant differences. The implantation rate was 40.4% in the CD group and 41.7% in the NVD group (p=0.842). The clinical pregnancy rate was 50% in the CD group and 49.3% in the NVD group (p=0.932), while the chemical pregnancy rate was 14.6% in the CD group and 19% in the NVD group (p=0.591). The miscarriage rates in the CD and NVD groups were 20% and 17.6%, respectively (p=0.803). One case of tubal ectopic pregnancy occurred in the NVD group (1.4%).
Conclusion
The mode of prior delivery did not significantly impact pregnancy outcomes following frozen-thawed embryo transfer.

Keyword

Cesarean section; Frozen embryo transfer; Embryo implantation; Intracytoplasmic sperm injection; Normal vaginal delivery