Korean J Gastroenterol.  2024 Jan;83(1):37-40. 10.4166/kjg.2023.143.

A Case of Primary Hepatic Leiomyoma Incidentally Found in a Middle-aged Woman without Underlying Diseases

Affiliations
  • 1Department of Surgery, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea


Figure

  • Fig. 1 Initial dynamic CT scan. (A, B) Abdominal CT scan demonstrating a 6.3 cm progressive enhancing mass in S7 (arrow) of the liver in portal phase (A) and venous phase (B).

  • Fig. 2 Dynamic MRI findings. (A) Hypointense signal on T1-weighted image. (B) Hyperintense signal on T2-weighted image. (C) Heterogeneously enhancement in the arterial phase. (D) Hypointense signal in hepatobiliary delayed phase.

  • Fig. 3 Gross pathologic findings. (A) Exophytic mass on S7 in operative field. (B) Gross finding of the tumor shows grayish white, solid, and whorled mass weighing 171 g and 7.5×4.2×4.0 cm.

  • Fig. 4 Hematoxylin and eosin stain, x100. The hepatic tumor was composed of bundles of spindle-shaped cells with nuclei and eosinophilic cytoplasm.

  • Fig. 5 Immunohistochemical examination. (A–D) Smooth muscle actin, x100 (A), KIT, x100 (B), CD34, x100 (C), and S100, x100 (D) were examined by immunohistochemistry.

  • Fig. 6 CT scan at postoperative 30th day. There were no abnormal findings except for small amount fluid collection at the resection margin.


Reference

1. Reinertson TE, Fortune JB, Peters JC, Pagnotta I, Balint JA. 1992; Primary leiomyoma of the liver. A case report and review of the literature. Dig Dis Sci. 37:622–627. DOI: 10.1007/BF01307591. PMID: 1551357.
2. Luo XZ, Ming CS, Chen XP, Gong NQ. 2013; Epstein-Barr virus negative primary hepatic leiomyoma: case report and literature review. World J Gastroenterol. 19:4094–4098. DOI: 10.3748/wjg.v19.i25.4094. PMID: 23840159. PMCID: PMC3703201.
3. Demel R. 1926; Ein operierter Fall von Leber-Myom. Virchows Arch Pathol Anat Physiol Klin Med. 261:881–884. DOI: 10.1007/BF01892215.
4. Prévot S, Néris J, de Saint Maur PP. 1994; Detection of Epstein Barr virus in an hepatic leiomyomatous neoplasm in an adult human immunodeficiency virus 1-infected patient. Virchows Arch. 425:321–325. DOI: 10.1007/BF00196156. PMID: 7812519.
5. Hollands MJ, Jaworski R, Wong KP, Little JM. 1989; A leiomyoma of the liver. HPB Surg. 1:337–343. DOI: 10.1155/1989/45978. PMID: 2487073. PMCID: PMC2423549.
6. Belli G, Ciciliano F, Lannelli A, Marano I. 2001; Hepatic resection for primary giant leiomyoma of the liver. HPB (Oxford). 3:11–12. DOI: 10.1080/136518201753173692. PMID: 18333008. PMCID: PMC2020611.
7. Santos I, Valls C, Leiva D, Serrano T, Martinez L, Ruiz S. 2011; Primary hepatic leiomyoma: case report. Abdom Imaging. 36:315–317. DOI: 10.1007/s00261-010-9648-y. PMID: 20959979.
8. Penn I. 1978; Malignancies associated with immunosuppressive or cytotoxic therapy. Surgery. 83:492–502.
9. Lee ES, Locker J, Nalesnik M, et al. 1995; The association of Epstein-Barr virus with smooth-muscle tumors occurring after organ transplantation. N Engl J Med. 332:19–25. DOI: 10.1056/NEJM199501053320104. PMID: 7990861.
10. Starzl TE, Nalesnik MA, Porter KA, et al. 1984; Reversibility of lymphomas and lymphoproliferative lesions developing under cyclosporin-steroid therapy. Lancet. 1:583–587. DOI: 10.1016/S0140-6736(84)90994-2. PMID: 6142304.
11. Jang SH, Kim SM, Sohn JS, Ryu KH, Yuk HB. 2016; A firm hepatic mass cannot be penetrated by US-guided needle biopsy. Clin Ultrasound. 1:126–129. DOI: 10.18525/cu.2016.1.2.126.
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