J Retin.  2022 Nov;7(2):75-81. 10.21561/jor.2022.7.2.75.

Evaluation of Electroretinograms Using RETeval ^TM in Preterm Infants without Retinopathy of Prematurity

• Jeong KD
• Park JY
• Park JM
• Kim JS
• Choi J
• Hwang JH

• KMID: 2552133
• DOI: http://doi.org/10.21561/jor.2022.7.2.75

Abstract

Purpose
This study was to conducted to evaluate the usefulness of light adapted electroretinography (ERG) using the RETeval ^TM system (LKC Technologies, Gaithersburg, MD, USA) in preterm infants without retinopathy of prematurity.
Methods
Overall, 18 preterm infants underwent light adapted ERG using the RETeval ^TM system without sedation. Readable results were acquired from 11 patients (61%) and the mean gestational age at birth was 33 ± 3 weeks.
Results
The amplitude and implicit time of the ‘a’ wave was -8.1 ± 6.6 µV and 17.3 ± 7.8 ms, respectively, while those of the ‘b’ wave was 20.4 ± 13.6 µV and 36.7 ± 8.8 ms, respectively. Additionally, 30-Hz flicker results were obtained with an amplitude and implicit time of 6.0 ± 3.8 µV and 32.3 ± 2.8 ms, respectively. Negative correlation was found between the ‘a’ wave amplitude and age at examination (p < 0.05). The light-adapted 3.0 ERG response was decreased in preterm infants and a larger decrease in ‘b’ wave amplitude than ‘a’wave amplitude was observed, which corresponds to the histological maturation of the retina.
Conclusions
Our study indicates that RETeval ^TM system is useful for evaluating retinal function in preterm infants.

Keyword

Electroretinography; Preterm infants; RETeval ^TM