Korean J Transplant.  2023 Nov;37(Suppl 1):S66. 10.4285/ATW2023.F-6421.

Is it really challenging procedure to performing the liver transplantations in polycystic liver disease?

• OH Rk
• Yoon YI

• KMID: 2551653
• DOI: http://doi.org/10.4285/ATW2023.F-6421

Abstract

Background
Liver transplantation (LT) is the only curative treatment option for polycystic liver disease (PCLD) and is associated with good survival rates. Patients with PCLD complain of discomfort due to very large liver volume, but liver function is preserved until a late stage. The aim of the study is to review our center experience in LT for PCLD.
Methods
This study was performed from Asan Medical Center LT database. It contains all patients transplanted for PCLD. Data was extracted for patients who underwent LT between February 2004 to February 2023 and follow up until May 31, 2023.
Results
Data of 13 PCLD patients who underwent LDLT between February 2004 to February 2023 were analyzed. Eleven (85%) of these patients were female. Seven (54%) of our database had PCLD while two (15.4%) had autosomal dominant polycystic kidney disease and one (7.6%) had autosomal recessive polycystic kidney disease. The median model for end-stage liver dis- ease score at time for referral was 10. The median age of transplant was 49.5 years for male vs. 55 for female patients. The median weight of the harvested liver was 3,830 g, and 11 (85%) of transplanted livers had an Rt. lobe was used. In just two (15%) cases, Lt. lobe was used. The mean graft-to-recipient weight ratio of the transplanted liver was 1.07. After a median follow-up of 94 months, the probability of survival was 92%. Comparing survival analysis between males and females did not show sig-nificant differences.
Conclusions
Most of the patients who received LT for PCLD were more women than men. Patients with PCLD complain of discomfort due to very large liver volume. After LT for PCLD had excellent survival rate.