Ann Lab Med.  2023 Jan;43(1):120-123. 10.3343/alm.2023.43.1.120.

Clinical Evaluation of Two Rapid Antigen Tests for Severe Acute Respiratory Syndrome Coronavirus 2 Detection

• Yu K
• Song J
• Kim D
• Park Y
• Jeong SH

• KMID: 2551616
• DOI: http://doi.org/10.3343/alm.2023.43.1.120

Figure

• 

  Fig. 1 Correlation between the results of rapid antigen tests for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigen and the cycle threshold (Ct) values of real-time PCR (RT-PCR). Correlation coefficients were calculated by Spearman’s rank test. Red triangles represent samples with positive RT-PCR results; and green circles indicate those with negative RT-PCR results. Although the manufacturer does not recommend semi-quantitative reading of the immunochromatographic assay, the results were classified as follows for study purposes only: trace, if paler than the control line; 1+, if similar to the control; 2+, if stronger than the control. (A) Correlation between the results of the immunochromatographic assay and RT-PCR Ct values (Spearman ρ=–0.848, 95% CI –0.870 to –0.822; P<0.001). (B) Correlation between the results of the fluorescence immunoassay and RT-PCR (Spearman ρ=–0.583, 95% CI –0.637 to –0.523; P<0.001). The yellow line indicates the default cut-off index (1.0) of the fluorescence immunoassay.

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